Nick Hart

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Nick Hart

Nich HartDr Nicholas Hart

  • Clinical and academic director of the Lane Fox Respiratory Unit at St Thomas’ Hospital
  • Reader in respiratory and critical care medicine at King’s College London (KCL)
  • Directorate research and development lead at Guy’s and St Thomas’ NHS Foundation Trust

Phone: 020 7188 86115



Region: London

Research type: Clinical

Research Interests:

  • Muscle wasting, weakness and rehabilitation
  • Advanced physiological monitoring and ventilatory strategies

Key Techniques: 

Keywords:  weaning, rehabilitation and home mechanical ventilation in patients with chronic respiratory failure


  • National Institute of Health Research
  • Medical Research Council
  • European Union
  • British Lung Foundation
  • Rosetree Foundation
  • Guy’s & St Thomas’ Charity
  • Number of unrestricted grants from industry partners.


Selected Publications:

  1. An Official American Thoracic Society Practice Guideline: The Diagnosis of Intensive Care Acquired Weakness in Adults. E Fan, RG Brower, F Cheek, L Chlan, R Gosselink, N Hart, MS Herridge, RO Hopkins, CL Hough, JP Kress, N Latronico, M Moss, DM Needham, MM Rich, RD Stevens, KC Wilson, C Winkelman, DW Zochodne and NA Ali. 2014. Am J Resp and Crit Care Med. 2014: [In Press]
  2. A UK Survey of Rehabilitation Following Critical Illness: Implementation of NICE Clinical Guidance 83 (CG 83) Following Hospital Discharge. BA Connolly, A Douiri, J Steier, J Moxham and N Hart. BMJ Open. 2014: [In Press]
  3. An Observational Cohort Study to Determine Efficacy, Adherence and Outcome of Early Initiation of Pressure Support Ventilation During Mechanical Ventilation. G Glover, BA Connolly, S Di Gangi, L Ayers M Terblanche R Beale and N Hart. BMJ Open Resp Res 2014: [In Press]
  4. Functional electrical stimulation with cycling in the critically ill: a pilot case-matched control study. SM Parry, S Berney, S Warrillow , D El-Ansary, A Bryant, Z Puthucheary, N Hart, R Koopman and L Denehy. Journal of Critical Care. 2014: [In Press]
  5. A Cohort Study To Identify Simple Clinical Tests for Chronic Respiratory Failure in Obese Patients with Sleep Disordered Breathing. S Mandal, E-S Suh, E Boleat, W Asher, M Kamalanathan, K Lee, A Douiri, PB Murphy, J Steier and N Hart. BMJ Open Resp Res 2014: 1: e000022. Doi: 10.1136/bmjresp-2014-000022
  6. Observational Study of the Effect of Obesity on Lung Volumes. J Steier, A Lunt, N Hart, MI Polkey and J Moxham. Thorax 2014: [In Press]
  7. The Effect of Post Operative Physical Training on Activity After Curative Surgery for Non-Small Cell Lung Cancer: A Multicentre Randomised Controlled Trial. G Arbane, C Speed, N Hart, A Douri, N Hopkispon, R Garrod. 2014. Physiotherapy. 100:100-7
  8. A Randomized Controlled Trial of ACE-inhibition for Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease. D Shrikrishna, R Tanner, J Lee, A Natanek, A Lewis, P Murphy, N Hart, J Moxham, H Montgomery, P Kemp, M Polkey, N Hopkinson. Chest. 2014: [In Press]
  9. Comparison of 7 vs. 14 days wrist actigraphy monitoring in a sleep disorders clinic population. S Briscoe, E Hardy, M Pengo, C Kosky, AJ Williams, N Hart, J Steier. 2014. Chronobiol Int. 31:356-62
  10. Acute Skeletal Muscle Wasting in Critical Illness. ZA Puthucheary, J Rawal, M McPhail, B Connolly, G Ratnayake, P Chan, N Hopkinson, R Padhke, T Dew, PS Sidhu, C Velloso, J Seymour, CC Agley, A Selby, M Limb, L Edwards, K Smith, A Rowlerson, MJ Rennie, J Moxham and SDR Harridge*, N Hart*, HE Montgomery*. 2013. JAMA. 10(15):1591-600
  11. *joint senior authors
  12. Clinical Predictive Value of Manual Muscle Strength Testing During Critical Illness: An Observational Cohort Study. BA Connolly, GD Jones, AA Curtis, PB Murphy, A Douiri, NS Hopkinson, MI Polkey, J Moxham and N Hart. 2013. Critical Care. 17(5):R229.
  13. Economic Assessment of Home-Based COPD Management Programs. S X Liu, M.D, MC. Lee, M Atakhorrami, J Tatousek, M McCormack, R Yung, N Hart & DP White. 2013. COPD. 10:640-9
  14. Provision of Home Mechanical Ventilation and Sleep Services Provision for England Survey. S Mandal, E Suh, M Davies, I Smith, T Maher, MW Elliott, AC Davidson and N Hart. 2013. Thorax. 68:880-1
  15. Low flow nocturnal oxygen therapy does not suppress haemoglobin levels in sickle cell disease. H Ip, R Kesse-Adu, J Howard & N Hart. 2013. Br J Haematol. 161:455-6
  16. Dysphagia in Duchenne Muscular Dystrophy assessed objectively by Surface Electromyography. S Rosenvinge, R Garrod, N Hart & S Miller. 2013. Dysphagia. 28(2):188-98
  17. Dysphagia in Duchenne Muscular Dystrophy assessed by Validated Questionnaire. S Rosenvinge, R Garrod, N Hart & S Miller. 2013. Int J Lang Commun Disord. 48: 240-46