Mike Grocott

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Mike Grocott

GrocottProfessor of Anaesthesia and Critical Care Medicine

Head, Integrative Physiology and Critical Illness Group, CES Lead, Critical Care Research Area, Southampton NIHR Respiratory BRU

Phone: (023) 8120 8449

Email: mike.grocott@soton.ac.uk

Address: Faculty of Medicine
University of Southampton
Southampton General Hospital
Mailpoint 801
South Academic Block
Tremona Road
SO16 6YD


Region: Southampton

Research type: Physiology

Research Interests:Human responses to hypoxia, oxygen transport and utilisation, measuring and improving outcome following surgery, acute lung injury, and fluid therapy

Key Techniques: 

Keywords:  Integrative Physiology, Hyopxia, perioperative medicine


Collaborations: Monty Mythen, Hugh Montgomery

Selected Publications:

  1. Martin, D.S., Cobb, A., Meale, P., Mitchell, K., Edsell, M., Mythen, M.G. and Grocott, M.P.W. Xtreme Alps Research Group (2014) Systemic oxygen extraction during exercise at high altitude. British Journal of Anaesthesia, 1-6. (doi:10.1093/bja/aeu404). (PMID:25501722).
  2. West, Malcolm A., Loughney, Lisa, Lythgoe, Daniel, Barben, Christopher P., Adams, Valerie L., Bimson, William E., Grocott, Michael P.W., Jack, Sandy and Kemp, Graham J. (2014) The effect of neoadjuvant chemoradiotherapy on whole-body physical fitness and skeletal muscle mitochondrial oxidative phosphorylation in vivo in locally advanced rectal cancer patients – an observational pilot study. PLoS ONE, 9, (12), 1-15. (doi:10.1371/journal.pone.0111526). (PMID:17440956).
  3. Levett, Denny Z.H., Viganò, Agnese, Capitanio, Daniele, Vasso, Michele, De Palma, Sara, Moriggi, Manuela, Martin, Daniel S, Murray, Andrew J., Cerretelli, Paolo, Grocott, Mike P.W. and Gelfi, Cecilia (2014) Changes in muscle proteomics in the course of the Caudwell Research Expedition to Mt. Everest. Proteomics, 1-12. (doi:10.1002/pmic.201400306). (PMID:25370915).
  4. Moonesinghe, S.R., Harris, S., Mythen, M.G., Rowan, K.M., Haddad, F.S., Emberton, M. and Grocott, M.P.W. (2014) Survival after postoperative morbidity: a longitudinal observational cohort study. British Journal of Anaesthesia, 113, (6), 977-84. (doi:10.1093/bja/aeu224).
  5. Dushianthan, Ahilanandan, Goss, Victoria, Cusack, Rebecca, Grocott, Michael P.W. and Postle, Anthony D. (2014) Altered molecular specificity of surfactant phosphatidycholine synthesis in patients with acute respiratory distress syndrome. Respiratory Research, 15, (1), 1-11. (doi:10.1186/s12931-014-0128-8). (PMID:25378080).
  6. West, M.A., Loughney, L., Barben, C.P., Sripadam, R., Kemp, G.J., Grocott, M.P.W. and Jack, S. (2014) The effects of neoadjuvant chemoradiotherapy on physical fitness and morbidity in rectal cancer surgery patients. European Journal of Surgical Oncology, 40, (11), 1421-1428. (doi:10.1016/j.ejso.2014.03.021). (PMID:24784775).
  7. Black, C., Grocott, M.P.W. and Singer, M. (2014) Metabolic monitoring in the intensive care unit: a comparison of the Medgraphics Ultima, Deltatrac II, and Douglas bag collection methods. British Journal of Anaesthesia (doi:10.1093/bja/aeu365). (PMID:25354946).
  8. Pearse, Rupert M., MacDonald, Neil and Grocott, Michael P.W. OPTIMISE Study Group (2014) Use of hemodynamic algorithm after gastrointestinal surgery – reply. JAMA, 312, (14), 1471. (doi:10.1001/jama.2014.10366). (PMID:25291591).
  9. Dushianthan, Ahilanandan, Cusack, Rebecca, Chee, Nigel, Dunn, John-Oliver and Grocott, Michael P.W. (2014) Perceptions of diagnosis and management of patients with acute respiratory distress syndrome: a survey of United Kingdom intensive care physicians. BMC Anesthesiology, 14, (87), 1-8. (doi:10.1186/1471-2253-14-87). (PMID:25309125).
  10. Jackson, Sarah E., West, M.A., Raw, D., Marwood, S., Ambler, G., Cope, T.M., Shrotri, M., Sturgess, R.P., Calverley, P.M.A., Ottensmeier, C.H. and Grocott, M.P.W. (2014) The effect of neoadjuvant chemotherapy on physical fitness and survival in patients undergoing oesophagogastric cancer surgery. European Journal of Surgical Oncology (EJSO), 40, (10), 1313-1320. (doi:10.1016/j.ejso.2014.03.010). (PMID:24731268).
  11. Dattani, Raj S., Swerner, Casey B., Wyatt, Lucy R., Kolfschoten, Nikki E., Edsell, Mark E.G., Imray, Christopher H.E., Grocott, Michael P.W., Montgomery, Hugh E and Wilson, Mark H. (2014) Pupil dynamics in hypoxic conditions: Caudwell Xtreme Everest results. High Altitude Medicine & Biology, 15, (3), 422-423. (doi:10.1089/ham.2014.1012). (PMID:25211649).
  12. West, M.A., Parry, M.G., Lythgoe, D., Barben, C.P., Kemp, G.J., Grocott, M.P.W. and Jack, S. (2014) Cardiopulmonary exercise testing for the prediction of morbidity risk after rectal cancer surgery. The British Journal of Surgery, 101, (9), 1166-1172. (doi:10.1002/bjs.9551). (PMID:24916313).
  13. Pearse, Rupert M., Harrison, David A., MacDonald, Neil, Gillies, Michael A., Blunt, Mark, Ackland, Gareth, Grocott, Michael P.W., Ahern, Aoife, Griggs, Kathryn, Scott, Rachael, Hinds, Charles, Rowan, Kathryn and UNSPECIFIED (2014) Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. JAMA The Journal of the American Medical Association, 311, (21), 2181-90. (24842135). (PMID:10.1001/jama.2014.5305).